Severe #COVID-19 in the young and healthy: monogenic inborn errors of immunity? | Nature Reviews Immunology
▻https://www.nature.com/articles/s41577-020-0373-7
Severe COVID-19 is rare in previously healthy individuals who are less than 50 years of age, affecting probably no more than 1 in 1,000 such infected individuals. We suggest that these patients may become critically ill because of monogenic inborn errors that disrupt protective immunity to SARS-CoV-2.