A booster is your best shot now - by Eric Topol
▻https://erictopol.substack.com/p/a-booster-is-your-best-shot-now
The idea that we could be looking annual shots is unrealistic given the waning period and lack of clearcut seasonal Covid as is the case with flu. That is why we desperately need new generation of vaccines that include nasal vaccines to block infections/transmission, more durable vaccines (such as by tweaking the nanoparticles) and pan-sarbecovirus vaccines that will be variant-proof. All of this is in our reach, but so far not getting the priority and resource allocation from the US to follow through.
For now, the best defense we have against the BQ.1.1-led wave is to get a booster. It will markedly raise neutralizing antibodies and our cellular immune response, and just-in-time to broaden our immunity to be ready for BQ.1.1 and related variants with marked immune evasiveness. As you well know, it takes a couple of weeks to get the immune response built, so this is the right time to get it done. It will help prevent severe Covid for at least 4-5 months ahead. Be ready. The pandemic isn’t over—yet. Preserve your health and that of your family, friends, and network.
