• Comment #Big_Pharma pénalise-t-il le traitement de l’épidémie des opiacés ? - Actualité Houssenia Writing
    https://actualite.housseniawriting.com/sante/2017/08/09/comment-big-pharma-penalise-t-il-le-traitement-de-lepidemie-des-opiaces/23013

    Traduction d’un article de The Conversation par Robin Feldman, professeure de propriété intellectuelle à l’université de Californie.

    Les grandes entreprises pharmacologiques (Big Pharma) utilisent de nombreuses tactiques pour retarder l’arrivée des #génériques et on peut prendre l’exemple des traitements contre l’épidémie des #opiacés.

    • En 2015, 80 % de la croissance des bénéfices des 20 plus grandes entreprises technologiques provenaient de l’augmentation des prix. Et les médicaments aux États-Unis sont largement plus chers que dans d’autres pays. Par exemple, le Syprine, un médicament contre l’insuffisante hépatique, coute moins de 400 dollars pour un an de traitement dans de nombreux pays. Aux États-Unis, ce médicament coute 300 000 dollars. Sovaldi, le médicament contre l’hépatite C de Gilead, coute environ 1 000 dollars à l’étranger. Aux États-Unis, il coute 84 000 dollars.

      Il faudra un motif d’inculpation pour trainer les gens qui décident cela devant la justice. Un truc du genre crime contre l’humanité.

    • Un des aspects intéressants des câbles diplomatiques américains, publiés par Wikileaks, c’était justement qu’une des activités principales des ambassades ricaines dans monde consiste à défendre les intérêts des grands groupes pharmaceutiques américaines.

      Par exemple (quasiment au hasard), ce câble de 2005 à ce sujet au Brésil :
      https://wikileaks.org/plusd/cables/05BRASILIA1567_a.html

      1. (C) Summary. Ambassador Hugueney of Brazil’s Foreign Ministry (Itamaraty) told Ambassador June 6 that U.S. pharmaceutical companies should improve their offers on pricing and/or voluntary licenses for AIDS treatment drugs so as to avoid compulsory licensing by the Ministry of Health (MoH). Hugueney believed movement in the Chamber of Deputies of legislation that would deny patentability to AIDS drugs was likely intended to provide greater leverage to the Ministry of Health in its negotiations with the pharmaceutical companies. The bill’s broad political backing, he observed, makes a presidential veto unlikely should the legislation pass. On the WTO Doha Round of trade negotiations, Hugueney said Brazil will submit a “substantially improved” revised services offer the week of June 6. Hugueney expects to take up the post of Brazil’s Ambassador to the WTO by late August or early September. Hugueney confirmed Brazil’s plan to attend the June 21 to 22 US-EU International Conference on Iraq. End Summary.

      2. (SBU) On June 6, Ambassador met with Clodoaldo Hugueney, Itamaraty’s Under Secretary for Economic and Technological Affairs, to discuss a number of trade issues, principally, pending legislation that would render drugs to prevent and treat AIDS un-patentable, and the continuing threat of compulsory licensing facing the U.S. pharmaceutical companies Gilead Sciences, Abbott Laboratories, and Merck, Sharp & Dohme for their AIDS treatment drugs (ref A). Hugueney was accompanied by his assistant, Miguel Franco, and Otavio Brandelli, Chief of the Ministry’s IPR Division. Ecouns, Commoff, and Econoff accompanied Ambassador.

      AIDS Drugs - Compulsory License Threat and Patent Legislation

      3. (C) Hugueney, who had just returned from Doha negotiations in Geneva, said Itamaraty is following MoH negotiations with the pharmaceutical companies closely and described them as boiling down to issues of pricing or voluntary license/royalty payments. He noted the intense pressure the GoB is under from civil society, particularly NGOs, to issue compulsory licenses. Hugueney agreed the best outcome would be to avoid compulsory licenses, but opined that to do so would require improved offers on price or voluntary licensing from the companies. (Upon relaying this message to the companies, the Merck representative here told us his company was in the process of preparing a more detailed offer, although he did not say that it would be more forthcoming on prices. As for Gilead and Abbott, they have taken Hugueney’s suggestion “under advisement.”) Hugueney further advised the companies to maintain a dialog with the MoH to forestall precipitous, politically motivated action by that Ministry, and encouraged them to explain/present their proposals to a wide array of GoB interlocutors.

  • Mathematical secrets of ancient #tablet unlocked after nearly a century of study | #Science | The Guardian

    https://www.theguardian.com/science/2017/aug/24/mathematical-secrets-of-ancient-tablet-unlocked-after-nearly-a-century-

    [...]

    “A treasure trove of Babylonian tablets exists, but only a fraction of them have been studied yet. The mathematical world is only waking up to the fact that this ancient but very sophisticated mathematical culture has much to teach us.”

    They suggest that the mathematics of Plimpton 322 indicate that it originally had six columns and 38 rows. They believe it was a working tool, not – as some have suggested – simply a teaching aid for checking calculations. “Plimpton 322 was a powerful tool that could have been used for surveying fields or making architectural calculations to build palaces, temples or step pyramids,” Mansfield said.

    As far back as 1945 the Austrian mathematician Otto Neugebauer and his associate Abraham Sachs were the first to note that Plimpton 322 has 15 pairs of numbers forming parts of Pythagorean triples: three whole numbers a, b and c such that a squared plus b squared equal c squared. The integers 3, 4 and 5 are a well-known example of a Pythagorean triple, but the values on Plimpton 322 are often considerably larger with, for example, the first row referencing the triple 119, 120 and 169.

    ||

    via https://diasp.eu/posts/5951983

    #mathématique #calculateur #antiquité #Babylone
    #trigonométrie