Association of air particulate #pollution with bone loss over time and bone fracture risk : analysis of data from two independent studies - The Lancet Planetary Health
▻http://www.thelancet.com/journals/lanplh/article/PIIS2542-5196(17)30136-5/abstract
Research in context
Evidence before this study
Exposure to particulate matter induces oxidative damage and inflammation, which might affect bone health, particularly of older populations. Smoking, which contains several components of particulate matter, has been consistently associated with bone damage. However, whether ambient particulate matter concentrations affect calcium metabolism, bone damage, and risk of fractures is uncertain.
Added value of this study
We demonstrate for the first time higher rates of hospital admissions for bone fractures in communities with higher ambient concentrations of particulate matter less than 2·5 μm in aerodynamic diameter. Participants living at addresses with higher concentrations of traffic-derived particulate matter exhibit lower serum parathyroid hormone concentrations and higher decreases in bone mineral density over an 8-year follow-up.
Implications of all the available evidence
This study provides evidence that long-term exposure to particulate matter—a persistent environmental issue in Europe and globally—is an independent risk factor for bone fractures, possibly involving changes in parathyroid hormone concentrations. These associations might disproportionately affect under-privileged communities. We found the association of particulate matter well below the annual average limits set by the US Environmental Protection Agency and the European Union. Improvements in particulate air pollution concentrations might ameliorate bone health, prevent bone fractures, and reduce the health cost burden associated with fractures in older individuals.
#Ostéoporose : un lien établi entre pollution atmosphérique et risque de fracture – Portail de la communauté guinéenne
▻http://kababachir.com/osteoporose-un-lien-etabli-entre-pollution-atmospherique-et-risque-de-fr
Au-delà du risque cardiovasculaire et respiratoire ou même de cancer, vivre longtemps dans une zone très polluée pourrait augmenter le risque de fracture liée à l’ostéoporose, surtout chez les seniors, indiquent deux nouvelles études américaines publiées dans la revueThe Lancet Planetary Health.
