WHO launches global megatrial of the four most promising coronavirus treatments | Science | AAAS
▻https://www.sciencemag.org/news/2020/03/who-launches-global-megatrial-four-most-promising-coronavirus-treatments
Scientists have suggested dozens of existing compounds for testing but WHO is focusing on what it says are the four most promising therapies: an experimental antiviral compound called #remdesivir; the malaria medications #chloroquine and #hydroxychloroquine; a combination of two HIV drugs, #lopinavir and #ritonavir; and that same combination plus #interferon-beta, an immune system messenger that can help cripple viruses. Some data on their use in COVID-19 patients has already emerged—the HIV combo failed in a small study in China-but WHO believes a large trial with a greater variety of patients is warranted.
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