Thread by stdebove : À un rythme d’à peu près 2 mutations par mois, le coronavirus continue sa petite évolution tranquillou (rassurez-vous, une très grande parti…
▻https://threadreaderapp.com/thread/1244351052448763909.html
À un rythme d’à peu près 2 mutations par mois, le coronavirus continue sa petite évolution tranquillou (rassurez-vous, une très grande partie de ces mutations n’a aucun effet sur la dangerosité du virus ! Mais elles nous permettent quand même de faire de la science dessus) 1/6
Par exemple en France, une grosse partie des virus reçus (et séquencés) nous sont arrivés par l’Angleterre. Le reste directement de Chine.
Nextstrain / ncov
▻https://nextstrain.org/ncov?f_country=France
Latest Nextstrain COVID-19 situation report in English and in other languages. Follow @nextstrain for continual updates to data and analysis.
This phylogeny shows evolutionary relationships of hCoV-19 (or SARS-CoV-2) viruses from the ongoing novel coronavirus COVID-19 pandemic. This phylogeny shows an initial emergence in Wuhan, China, in Nov-Dec 2019 followed by sustained human-to-human transmission leading to sampled infections. Although the genetic relationships among sampled viruses are quite clear, there is considerable uncertainty surrounding estimates of transmission dates and in reconstruction of geographic spread. Please be aware that specific inferred transmission patterns are only a hypothesis.
Site numbering and genome structure uses Wuhan-Hu-1/2019 as reference. The phylogeny is rooted relative to early samples from Wuhan. Temporal resolution assumes a nucleotide substitution rate of 8 × 10^-4 subs per site per year. Full details on bioinformatic processing can be found here.
Phylogenetic context of nCoV in SARS-related betacoronaviruses can be seen here.
We gratefully acknowledge the authors, originating and submitting laboratories of the genetic sequence and metadata made available through GISAID on which this research is based. A full listing of all originating and submitting laboratories is available below. An attribution table is available by clicking on “Download Data” at the bottom of the page and then clicking on “Strain Metadata” in the resulting dialog box.