Should scientists infect healthy people with the #coronavirus to test vaccines?
▻https://www.nature.com/articles/d41586-020-00927-3
You would start only after some preliminary testing to ensure that a vaccine candidate is safe and that it accomplishes an immune response in humans. You then gather a group of people at low risk from any exposure — young and relatively healthy individuals — and ensure that they are not already infected. You give them either the vaccine candidate or a placebo and wait for enough time for an immune response. And then you expose them to the virus.