#SARS-CoV-2 detection in different respiratory sites : A systematic review and meta-analysis - EBioMedicine
▻https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(20)30278-4/abstract
Le PCR dans les expectorations comporte moins de faux négatifs que dans les prélèvements classiques (naso-pharyngés).
Compared to nasopharyngeal swab sampling, sputum testing resulted in significantly higher rates of SARS-CoV-2 RNA detection while oropharyngeal swab testing had lower rates of viral RNA detection. Earlier sampling after symptom onset was associated with improved detection rates, but the differences in SARS-CoV-2 RNA detection by sampling method was consistent regardless of the duration of symptoms.