Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine : a pooled analysis of four randomised trials - The Lancet
▻https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00432-3/abstract
Différer la dose de rappel du #vaccin astra-zeneca/Oxford à 3 mois dans l’optique de pallier à la pénurie des #vaccins non seulement ne nuirait pas à son efficacité mais l’améliorerait.
A 3-month dose interval might have advantages over a programme with a short dose interval for roll-out of a pandemic vaccine to protect the largest number of individuals in the population as early as possible when supplies are scarce, while also improving protection after receiving a second dose.