medicalcondition:cancer

  • What These Medical Journals Don’t Reveal: Top Doctors’ Ties to Industry
    https://www.nytimes.com/2018/12/08/health/medical-journals-conflicts-of-interest.html

    One is dean of Yale’s medical school. Another is the director of a cancer center in Texas. A third is the next president of the most prominent society of cancer doctors.

    These leading medical figures are among dozens of doctors who have failed in recent years to report their financial relationships with pharmaceutical and health care companies when their studies are published in medical journals, according to a review by The New York Times and ProPublica and data from other recent research.

    #pharma #conflits_d_intérêts #transparence


  • Felicia Langer. Remembering Israel’s human rights law trailblazer, a Holocaust survivor who called to boycott Israeli products

    A communist labeled ’the terrorists’ attorney,’ Felicia Langer called her clients ‘resistance fighters.’ In 1990 she gave up and left for Germany, where she died over the summer

    Ofer Aderet SendSend me email alerts
    Nov 06, 2018

    https://www.haaretz.com/israel-news/.premium-remembering-israel-s-human-rights-law-trailblazer-1.6632132

    After the Six-Day War, attorney Felicia Langer opened an office near the Old City in Jerusalem and began representing Arabs. Langer was a strange type in the local topography: a Jewish Holocaust survivor with a Polish accent who adhered to European manners and believed in the ideology of communism.
    “Her engagement with Palestinians from the West Bank and Gaza Strip was perhaps the strangest thing in the Middle East,” wrote attorney Michael Sfard. Her acquaintances saw in her a pathfinder in legal battles that advanced the human rights of Palestinians. Her enemies saw in her a traitor and accessory of terrorists.
    >> Holocaust survivor and Palestinians’ rights lawyer Felicia Langer dies in exile at 87
    She was born in the city of Tarnov, Poland in 1930 as Felicia Amalia White. In World War II she fled with her family to the Soviet Union, where her father died. After the war, she returned to the land of her birth and married Holocaust survivor Moshe Langer. In 1950 they immigrated to Israel – “not because of Zionist ideology,” according to her, but to live near her mother.
    Archival documents attest to the tense relationships between her and the Israeli establishment. In 1968 an intelligence officer in the military government in Hebron testified before the Legal Attaché of the West Bank that she “held extreme left-wing opinions.” In 1975, the Foreign Ministry reported that the Shin Bet security service viewed her legal activities as being guided by political motivations to harm “the state and the image of the state.” She faced threats to her life throughout her career. Occasionally, she felt compelled to hire a bodyguard.
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    Langer fought the expulsion of Palestinian leaders, housing demolitions of terror suspects, administrative detentions (imprisonment without charges), and torture. “She never hesitated to accuse the establishment of crimes and to represent her clients as victims of an evil regime,” wrote Sfard.

    When they called her “the defense attorney of terrorists,” she replied that her clients were not terrorists, but “resistance fighters.” “A people under occupation has the right to wage violent struggle,” she said. Among her famous clients was the mayor of Nablus, Bassam Shakaa, one of the leaders of resistance to the occupation, whose expulsion Langer succeeded in preventing. Other clients included the parents of the attackers of Bus 300, who sought to sue the state for killing their sons, and a young Dutch woman who was detained at Ben-Gurion International Airport after she gathered intelligence for the Popular Front for the Liberation of Palestine. Langer maintained that she was just a “small cog.”
    In 1990, she immigrated to Germany, after handling what she estimated to have been 3,000 cases. “I could no longer help the Palestinian victims in the framework of the existing legal system and its flouting of international law, which is supposed to protect the people that I defended,” she said in an interview with Eran Torbiner. “It is forbidden to be silent; silence also can kill,” she said, in explaining her call for the boycott of Israeli goods. As a German citizen, she called on Germany to fight the occupation.
    Langer lived in Tübingen, teaching and writing books. Critics were angered by her comparison of Israel to the Nazis, and accused her of hypocrisy for ignoring the crimes of communist regimes. When she was asked once to describe her “love of homeland,” she answered: “Hatred of occupation.” In June, Langer died of cancer at age 87.

    Ofer Aderet
    Haaretz Correspondent


  • Hardy Fox, cofondateur et compositeur des Residents, longtemps anonyme, est mort
    https://www.lemonde.fr/disparitions/article/2018/11/03/le-cofondateur-et-compositeur-des-residents-longtemps-anonyme-est-mort_53784

    Le musicien américain Hardy Fox, cofondateur du groupe d’avant-garde #The_Residents, est mort mardi à l’âge de 73 ans des suites d’un cancer du cerveau. La nouvelle a été annoncée sur son site internet.

    Celui qui a été pendant plus de quatre décennies le clavier du groupe sous le pseudonyme de Charles Bobuck avait déjà dû renoncer à jouer avec lui en 2015, pour raisons de santé. Il en restait cependant le principal compositeur.

    The Residents fait ses débuts sur scène en 1971, et publie son premier album en 1974. Son nom (Meet the Residents) et sa pochette parodient ceux d’un album des Beatles sorti dix ans plus tôt.

    Plus que pour sa musique, satirique et avant-gardiste, les Residents sont connus du grand public pour leurs costumes sans lesquels ils n’apparaissent jamais. Le plus emblématique : un smoking et un masque en forme de globe oculaire géant, surmonté d’un chapeau haut-de-forme.

    #Fox_is_dead


  • Study of Cellphone Risks Finds ‘Some Evidence’ of Link to #Cancer, at Least in Male Rats - The New York Times
    https://www.nytimes.com/2018/11/01/health/cellphone-radiation-cancer.html

    For decades, health experts have struggled to determine whether or not cellphones can cause cancer. On Thursday, a federal agency released the final results of what experts call the world’s largest and most costly experiment to look into the question. The study originated in the Clinton administration, cost $30 million and involved some 3,000 rodents.

    The experiment, by the National Toxicology Program, found positive but relatively modest evidence that radio waves from some types of cellphones could raise the risk that male rats develop brain cancer.

    “We believe that the link between radio-frequency radiation and tumors in male rats is real,” John Bucher, a senior scientist at the National Toxicology Program, said in a statement.

    But he cautioned that the exposure levels and durations were far greater than what people typically encounter, and thus cannot “be compared directly to the exposure that humans experience.” Moreover, the rat study examined the effects of a radio frequency associated with an early generation of cellphone technology, one that fell out of routine use years ago. Any concerns arising from the study thus would seem to apply mainly to early adopters who used those bygone devices, not to users of current models.

    #cellulaires




  • Linguistic red flags from Facebook posts can predict future depression diagnoses — ScienceDaily
    https://www.sciencedaily.com/releases/2018/10/181015150643.htm

    Research finds that the language people use in their Facebook posts can predict a future diagnosis of depression as accurately as the tools clinicians use in medical settings to screen for the disease.

    In any given year, depression affects more than 6 percent of the adult population in the United States — some 16 million people — but fewer than half receive the treatment they need. What if an algorithm could scan social media and point to linguistic red flags of the disease before a formal medical diagnosis had been made?

    Ah oui, ce serait fantastique pour les Big Pharma : la dépression est une maladie complexe, dont les symptômes graves sont souvent confondus avec la déprime qui est un état sychologique que nous connaissons tous. Notre Facebook, couplé avec notre assistant vocal Amazon nous gorgerait de Valium, et tout irait pour le mieux dans le Meilleur des mondes.

    Considering conditions such as depression, anxiety, and PTSD , for example, you find more signals in the way people express themselves digitally."

    For six years, the WWBP, based in Penn’s Positive Psychology Center and Stony Brook’s Human Language Analysis Lab, has been studying how the words people use reflect inner feelings and contentedness. In 2014, Johannes Eichstaedt, WWBP founding research scientist, started to wonder whether it was possible for social media to predict mental health outcomes, particularly for depression.

    “Social media data contain markers akin to the genome,” Eichstaedt explains. “With surprisingly similar methods to those used in genomics, we can comb social media data to find these markers. Depression appears to be something quite detectable in this way; it really changes people’s use of social media in a way that something like skin disease or diabetes doesn’t.”

    Il y a au moins une bonne nouvelle sur la déontologie scientifique :

    Rather than do what previous studies had done — recruit participants who self-reported depression — the researchers identified data from people consenting to share Facebook statuses and electronic medical-record information, and then analyzed the statuses using machine-learning techniques to distinguish those with a formal depression diagnosis.

    Les marqueurs considérés sont aussi des marqueurs sociaux et économiques, qu’il faudrait traiter autrement qu’avec des médicaments.

    They learned that these markers comprised emotional, cognitive, and interpersonal processes such as hostility and loneliness, sadness and rumination, and that they could predict future depression as early as three months before first documentation of the illness in a medical record.

    La conclusion est fantastique : il faut rendre le balayage obligatoire !!!

    Eichstaedt sees long-term potential in using these data as a form of unobtrusive screening. “The hope is that one day, these screening systems can be integrated into systems of care,” he says. “This tool raises yellow flags; eventually the hope is that you could directly funnel people it identifies into scalable treatment modalities.”

    Despite some limitations to the study, including its strictly urban sample, and limitations in the field itself — not every depression diagnosis in a medical record meets the gold standard that structured clinical interviews provide, for example — the findings offer a potential new way to uncover and get help for those suffering from depression.

    #Dépression #Facebook #Foutaises #Hubris_scientifique #Big_pharma #Psychologie



  • Offline: Why has global health forgotten cancer? - The Lancet
    https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)32162-7/abstract

    Nothing illustrates the embedded irrationality of global health more than our attitudes to cancer. In 2016, according to the Global Burden of Disease, 8·9 million people died from cancer (23% of total worldwide deaths from NCDs, and 16% of deaths from all causes). The leading causes of cancer death are tumours of the trachea, bronchus, and lung (1·7 million deaths); gynaecological cancers (breast, cervix, ovary, and uterus: 1 million deaths); gastric cancer (834 000 deaths); colorectal cancer (829 600 deaths); and liver cancer (828 000 deaths). So why the indifference?

    The NCD community has become trapped in an ideology that privileges prevention over treatment. A similar mistake disfigured the early response to AIDS. I can recall senior WHO leaders two decades ago agreeing that a generation of people living with HIV would have to die before the pandemic could be controlled by prevention. Only anger and activism overturned the complacency of traditional public health practice. But the NCD community has no time for anger or activism

    #cancer #OMS #prévention #traitement (again)


  • United States Patent : 9861628
    http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=98,61,628.PN.&OS=PN/98,61,628&RS=PN/98,61,628

    Buprenorphine-wafer for drug substitution therapy

    Abstract

    The present invention relates to oral pharmaceutical dosage forms comprising buprenorphine with the dosage form releasing buprenorphine instantly upon oral, preferably sublingual, application of the dosage form. The present invention also relates to the use of such dosage forms for treating pain in a human or animal or for drug substitution therapy in drug-dependent human subjects.

    BACKGROUND OF THE INVENTION

    Chronic pain, which may be due to idiopathic reasons, cancer or other diseases such as rheumatism and arthritis, is typically treated with strong opioids.

    Over the last decades prejudices in the medical community as to the use of strong opioids for treating chronic pain in patients has significantly decreased. Many of the se prejudices were due to some of the characteristics being inherent to opioids.

    While opioids have always been known to be useful in pain treatment, they also display an addictive potential in view of their euphorigenic activity. Thus, if opioids are taken by healthy human subjects with a drug seeking behaviour they may lead to psychological as well as physical dependence.

    These usually undesired characteristics of opioids can however become important in certain scenarios such as drug substitution therapies for drug addicts. One of the fundamental problems of illicit drug abuse by drug addicts (“junkies”) who are dependent on the constant intake of illegal drugs such as heroin is the drug-related criminal activities resorted to by such addicts in order to raise enough money to fund their addiction. The constant pressures upon addicts to procure money for buying drugs and the concomitant criminal activities have been increasingly recognised as a major factor that counteracts efficient and long-lasting withdrawal and abstinence from drugs.

    Therefore, programmes have been developed, particularly in the United States and western European countries, in which drug addicts are allowed to take prescription drugs under close supervision of medical practitioners instead of illegal drugs such as street heroin.

    The aim of drug substitution theory is thus to first enable addicts to lead a regular life by administering legal drugs to prevent withdrawal symptoms, but because of their legal character and prescription by medical practitioners do not lead to the aforementioned described drug-related criminal activities. In a second and/or alternate step in the treatment of drug addiction may be to slowly make the drug addict less dependent on the drug by gradually reducing the dose of the substitution drug or to bridge the time until a therapy place in a withdrawal programme is available.

    The standard drug used in drug substitution therapy programmes has for a long time been methadone. However, in recent years the potential of other opioids as substitution drugs in substitution therapy has been recognised. A particularly suitable drug for that purpose is the opioid buprenorphine, which is a mixed opioid agonist/antagonist.

    Nowadays, buprenorphine preparations are administered in drug substitution programmes in the form of a tablet for sublingual administration. One of the reasons that the tablets are formulated for sublingual administration is that this the preferred route of administration for buprenorphine. Furthermore, if a patient swallows such tablets they will not provide euphorigenic activity.

    One example of sublingual tablets for drug substitution therapy is the preparation Subutex.RTM. (being marketed in Germany by Essex Pharma).

    Nevertheless, drug addicts sometimes still try to divert these sublingual buprenorphine tablets by removing them from the mouth when the supervising healthcare professional’s attention is directed to other activities. Later the tablets may be sold or the active agent buprenorphine isolated/extracted to apply it parenterally.

    Another buprenorphine preparation aimed at preventing this potential possibility of abuse has recently gained administrative approval in the United States (Suboxone.RTM.). The Suboxone.RTM. preparation comprises buprenorphine hydrochloride and the opioid antagonist naloxone hydrochloride dihydrate. The presence of naloxone is intended to prevent parenteral abuse of buprenorphine as parenteral co-administration of buprenorphine and naloxone in e.g. an opioid-dependent addict will lead to serious withdrawal symptoms.

    However, there remains a need for other diversion and/or abuse-resistant dosage forms of buprenorphine, which can be used in drug substitution therapy as described above. Additionally, it would be desirable to have a buprenorphine preparation available which is diversion and/or abuse-resistant in cases where the preparation is used for drug substitution therapy and which could also provide efficient analgesia in cases where the preparation is administered to alleviate pain in a patient.

    OBJECT AND SUMMARY OF THE INVENTION

    It is an object of the present invention to provide an oral pharmaceutical dosage form of the active agent buprenorphine that is less prone to diversion and/or abuse in drug substitution therapy. It is another object of the present invention to provide an oral dosage form of the active agent buprenorphine that can be used for drug substitution therapy and/or pain treatment.

    In one embodiment the present invention relates to an oral pharmaceutical dosage form comprising at least buprenorphine or a pharmaceutically acceptable salt thereof with a dosage form releasing buprenorphine or said pharmaceutically acceptable salt thereof instantly upon or oral, preferably sublingual, application of the dosage form. It is, however, understood that the invention and its various embodiments which are set out below, can be extended to any opioid or analgesic whose preferred route of administration is oral, prefereably sublingual, as is the case for buprenorphine.

    An instant release of buprenorphine or a pharmaceutically acceptable salt thereof upon oral, preferably sublingual, application means that substantially all of the buprenorphine or said pharmaceutically acceptable salt thereof will be released within less than three minutes, preferably within less than two minutes or less than one minute. Even more preferably, substantially all of the buprenorphine or said pharmaceutically acceptable salt thereof will be released within less than thirty seconds, twenty seconds, ten seconds or even within less than five seconds after oral, preferably sublingual, application of the dosage form. In one of the preferred embodiments these oral dosage forms will comprise between approximately 0.1 mg and approximately 16 mg buprenorphine or the equivalent amounts of a pharmaceutically acceptable salt thereof.

    In a further preferred embodiment these oral pharmaceutical dosage forms will achieve an average C.sub.max of between 1.5 ng/ml and approximately 2.25 ng/ml in the case of a dose of 0.4 mg buprenorphine hydrochloride being administered. In the case of a dose of 8 mg buprenorphine HCl being administered, the C.sub.max will typically be between approximately 2.5 and 3.5 ng/ml and if a dose of 16 mg buprenorphine hydrochloride is administered the C.sub.max will preferably be between 5.5 to 6.5 ng/ml.

    Yet another preferred embodiment of the invention relates to oral pharmaceutical dosage forms which may provide for the above-mentioned characteristics and/or an average Tmax of from approximately 45 to approximately 90 minutes.

    In a particularly preferred embodiment the dosage forms will additionally comprise an opioid antagonist, preferably naloxone or a pharmaceutically acceptable salt thereof.

    In yet a further preferred embodiment, the pharmaceutical dosage form will comprise buprenorphine and the opioid antagonist, which preferably is naloxone, in a weight ratio of from approximately 1:1 to approximately 10:1.

    One embodiment of the present invention also relates to oral pharmaceutical dosage forms, which may have some or all of the aforementioned characteristics and wherein the dosage form has a film-like or wafer-like shape.

    Another embodiment relates to a method of manufacturing the afore-mentioned described dosage forms.

    Embodiments of the present invention also relate to the use of the afore-described oral, preferably sublingual, pharmaceutical dosage forms in the manufacture of a medicament for treating pain in a human or animal and/or for drug substitution therapy in drug-dependent human subjects.

    One aspect of the invention also relates to a method of drug substitution therapy in drug-dependent human subjects wherein the aforementioned oral pharmaceutical dosage forms are administered to a drug-dependent subject in need thereof.

    #Opioides #Sackler #Brevet #Cynisme #Capitalisme_sauvage



  • Vitamin D, the Sunshine Supplement, Has Shadowy Money Behind It - The New York Times
    https://www.nytimes.com/2018/08/18/business/vitamin-d-michael-holick.html

    Enthusiasm for vitamin D among medical experts has dimmed in recent years, as rigorous clinical trials have failed to confirm the benefits suggested by early, preliminary studies. A string of trials has found no evidence that vitamin D reduces the risk of cancer, heart disease or falls in the elderly. And most scientists say there isn’t enough evidence to know if vitamin D can prevent chronic diseases that aren’t related to bones.

    Although the amount of vitamin D in a typical daily supplement is generally considered safe, it is possible to take too much. In 2015, an article in the American Journal of Medicine linked blood levels as low as 50 nanograms per milliliter with an increased risk of death. That’s within the level considered healthy by the Endocrine Society, which defined vitamin D “sufficiency” as between 30 and 100 nanograms, Rosen said.

    #corruption #conflit_d’intérêt #santé #pharma #vitamine_D



  • Australia’s Drought - The cancer eating away at farms
    https://fingfx.thomsonreuters.com/gfx/rngs/AUSTRALIA-DROUGHT/010071MC33G/index.html

    While the weather has improved in parts of Western Australia, winter rain has gone missing across much of the country’s east, leaving farmers praying for rain after planting seed in dry soil or culling cattle and sheep they can no longer afford to feed.

    (l’analogie avec le cancer est un peu dommage, mais à part ça) #reportage #carto et #drone très réussi


  • How to Win the War on Cancer - YouTube
    https://www.youtube.com/watch?v=l_C26gt1LbA

    How effective is chemotherapy for colon, lung, breast, and prostate cancer?

    https://nutritionfacts.org/video/how-to-win-the-war-on-cancer

    If you look at the contribution of cancer-killing chemo to five-year survival in cancer patients, it’s on the order of only about 2%. Now, there’s some pediatric cancers we’ve gotten good at treating, and testicular cancer and Hodgkin’s disease are exceptions, but if you look at our most common cancers—colon, lung, breast, and prostate—the success rate is only about 1%. Meaning like, out of nearly 14,000 colon cancer patients, only 146 lived out five years thanks to chemotherapy. So, the chance of survival benefit is like one in a hundred, but doctors don’t tell patients that. “…[N]ew chemotherapy drug[s are] promoted as…major breakthrough[s], only to be later [quietly] rejected.” “The minimal impact on survival in the more common cancers conflicts with the perceptions of many patients who feel they are receiving a treatment that will significantly enhance their chances of cure.”

    #cancer #chimiothérapie #prévention #nutritionfacts


  • Why #cbd Needs to be Part of Your Medical Regimen
    https://hackernoon.com/why-cbd-needs-to-be-part-of-your-medical-regimen-2ba8c5329b52?source=rss

    In a world where prescriptions are king and synthetic pharmaceuticals rule the medical community, finding reliable natural or homeopathic remedies can be a challenge. However for patients who have not found solutions for their conditions from “traditional” treatment, CBD, or Cannabidiol, has been something of a miracle cure. Reacting directly with the serotonin receptors in the body, CBD helps restore these natural neurotransmitters, helping the body to help itself.For individuals who suffer from minor motion sickness, chronic vertigo, and even chemotherapy related nausea, CBD treats these symptoms effectively and safely. One in four cancer patients, traditional treatments to manage nausea and vomiting have little to no effect. In these individuals, doses of CBD have been shown to (...)

    #cbd-oils #health #cannabis #infographics


  • PACE - Resolution 2071 (2015) - Public health and the interests of the pharmaceutical industry: how to guarantee the primacy of public health interests?
    http://assembly.coe.int/nw/xml/XRef/Xref-XML2HTML-en.asp?fileid=22154&lang=en

    During the 20th century, humankind saw the most spectacular medical advances in its history. Scientific progress helped us to identify the origin of countless illnesses and to develop treatments which have significantly improved the population’s state of health. The pharmaceutical industry has played an indisputable role here by investing massively in research and development for new medicines. It continues to do so and is therefore one of the key players in the health field and at the same time a very important sector of activity in many countries.
    2. For a long time, questions have been raised about the possible negative effects of the interaction between the pharmaceutical industry and health sector stakeholders. This interaction may well give rise to conflicts of interest, have an influence on the knowledge and behaviour of the players involved and result in biased decisions. In its Resolution 1749 (2010) “Handling of the H1N1 pandemic: more transparency needed”, the Parliamentary Assembly had expressed its concern at the risk of conflicts of interest among experts involved in sensitive health-related decisions.
    3. Despite the considerable progress made in preventing and dealing with conflicts of interest, this is still today largely a matter of hit-and-miss. By means of a self-regulation policy, the pharmaceutical industry is now adopting a much more ethical approach and legislation lays down rules in this area. However, self-regulation is not binding and the implementation of legislation leaves much to be desired.
    4. Research and development for new therapeutic molecules is a costly and lengthy process. In return for this investment, pharmaceutical companies benefit from an intellectual property right on the molecules they develop, protected by a patent. This innovation model has led to the discovery of thousands of medicines. However, more and more voices are now being heard arguing that this is not the optimal approach in public health matters.
    5. In recent years, in spite of the increase in the number of new medicines placed on the market, there have been very few that present a real therapeutic benefit, satisfying real health needs. In addition, we have seen an upsurge in the price of medicines, allegedly justified by the cost of research and development, which nonetheless remains opaque and broadly disputed. The exorbitant price of cancer and hepatitis C treatments is of particular concern. Public health systems are faced with constant cost increases in this area, jeopardising their ability to fulfil their role.

    #Pharmacie


  • We should be saluting the Gaza Strip
    The spirit of Gaza is unbroken by any siege and breathing life into the desperate and lost cause of the Palestinian struggle
    Gideon Levy | Jul 15, 2018 2:28 AM Haaretz.com
    https://www.haaretz.com/opinion/.premium-we-should-be-saluting-the-gaza-strip-1.6270636

    Were it not for the Gaza Strip, the occupation would have been long forgotten. Were it not for the Gaza Strip, Israel would have erased the Palestinian problem from its agenda and continued on blithely with its crimes and annexations, with its routine, as if 4 million people were not living under its heel. Were it not for the Gaza Strip, the world would also have forgotten. Most of it already has. This is why we must now salute the Gaza Strip — mainly the spirit of the Gaza Strip, the only one that is still breathing life into the desperate and lost cause of the Palestinian struggle for liberty.

    The resolute struggle of the Gaza Strip should also spark admiration in Israel. The handful of people with a conscience who still remain here should give thanks to the unbroken spirit of the Gaza Strip. The spirit of the West Bank crumpled after the failure of the second intifada, as did the spirit of the Israeli peace camp — most of which shattered long ago. Only the spirit of the Gaza Strip stands steadfast in its struggle.

    And so, anyone who does not want to forever live in an evil country must respect the embers that the young people of the Gaza Strip are still trying to stoke. Were it not for the kites, the fires, the Qassam rockets, the Palestinians would have entirely exited the awareness of everyone in Israel. Only the World Cup and the Eurovision Song Contest would hold any interest. Were it not for the blackened fields in the south, there would be a huge white flag fluttering not only over the Gaza Strip but over the entire Palestinian people. Seekers of justice, including in Israel, cannot wish for this kind of submission.

    It’s difficult, even insolent, to write these words from tranquil and secure Tel Aviv, following one more sleepless and nightmarish night in the south, but all days and nights in the Gaza Strip are much more difficult due to Israel’s inhumane policy, supported by most of its citizens, including people who live in the south. They don’t deserve to shoulder the burden but every struggle exacts a price from innocent victims, who we wish do not become casualties. One should remember that only Palestinians are being killed. On Saturday, the 139th victim of Israeli fire along the border died. He was 20. On Friday a 15-year-old boy was killed. The Gaza Strip is paying the full price in blood. This doesn’t cause it to desist. That is its spirit. One cannot but admire it.

    The spirit of the Gaza Strip is unbroken by any siege. The evil ones in Jerusalem shut down the Kerem Shalom border crossing, and Gaza shoots. The malicious ones in the Kirya government complex in Tel Aviv prevent young people from receiving medical treatment in the West Bank in order to save their legs from being amputated.

    For years they have been preventing cancer patients, including women and children, from receiving lifesaving treatment. Only 54 percent of requests to leave the Gaza Strip for medical reasons were approved last year, compared to 93 percent in 2012. That is wicked. One should read the letter written in June by 31 Israeli oncologists who called for a cessation of the abuse of Gaza women with cancer whose applications for exit permits take months to process, sealing their fates.

    The 31 rockets fired into Israel from the Gaza Strip Friday night are a restrained response to this malice. They are no more than a muted reminder of the fate of the Gaza Strip, addressed to those who think that 2 million people can be treated like this for over 10 years while continuing as if nothing was happening.

    The Gaza Strip has no choice. Nor does Hamas. Any attempt to pin the blame on the organization — which I only wish was more secular, more feminist and more democratic — is an evasion of responsibility. It wasn’t not Hamas that closed the Gaza Strip. Nor did the Gaza Strip’s inhabitants close themselves off. Israel (and Egypt) did it. Every hesitant attempt by Hamas to make some progress with Israel is immediately answered by automatic Israeli refusal. Nor is the world willing to talk with them, who knows why.

    All that’s left are the kites, which might lead to another round of merciless bombing and shelling by Israel, that Israel of course does not want. But what choice does the Gaza Strip have? A white flag of surrender over its fences, like the one the Palestinians in the West bank raised? A dream of a green island off the coast of the Mediterranean, which Israeli Transportation Minister Yisrael Katz will build for them? The struggle is the only path remaining, a path that should be respected, even if you are an Israeli who might be its victim.

    #GAZA


    • Merck Is Lowering Drug Prices. There’s a Catch. - The New York Times
      https://www.nytimes.com/2018/07/19/health/merck-trump-drug-prices.html

      The drugmaker Merck said Thursday that it would lower prices on several drugs by 10 percent or more, but its rollback affects minor products and would not lower the cost of its top-selling, expensive cancer and diabetes products.

      The move follows recent announcements by Pfizer and Novartis that they would freeze price increases for the rest of the year, as the industry confronts sustained criticism from President Trump, lawmakers and the public over the rising cost of prescriptions.

      Merck’s action shows just how cautiously the industry is shifting strategies: It did not cut the prices of any blockbusters like the cancer treatment Keytruda or the diabetes drug Januvia. Instead, it said it would reduce by 60 percent the list price of Zepatier, a hepatitis C drug whose recent sales have dipped so low that, after paying after-the-fact rebates to insurers, the company recorded no sales in the United States for the product in the first quarter of this year.

      The six other products that Merck said it was discounting were drugs that had lost their patent protection and are available from other manufacturers as low-cost generics.


  • U.S. Opposition to Breast-Feeding Resolution Stuns World Health Officials - The New York Times
    https://www.nytimes.com/2018/07/08/health/world-health-breastfeeding-ecuador-trump.html

    American officials sought to water down the resolution by removing language that called on governments to “protect, promote and support breast-feeding” and another passage that called on policymakers to restrict the promotion of food products that many experts say can have deleterious effects on young children.

    When that failed, they turned to threats, according to diplomats and government officials who took part in the discussions. Ecuador, which had planned to introduce the measure, was the first to find itself in the cross hairs.

    The Americans were blunt: If Ecuador refused to drop the resolution, Washington would unleash punishing trade measures and withdraw crucial military aid. The Ecuadorean government quickly acquiesced.

    #Etats-Unis #corrompu #corruption #lobbying #gangsters #mafia #sans_vergogne

    • Health advocates scrambled to find another sponsor for the resolution, but at least a dozen countries, most of them poor nations in Africa and Latin America, backed off, citing fears of retaliation, according to officials from Uruguay, Mexico and the United States.

    • Breastfeeding: achieving the new normal - The Lancet
      https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)00210-5/abstract

      The deaths of 823 000 children and 20 000 mothers each year could be averted through universal breastfeeding, along with economic savings of US$300 billion. The Series confirms the benefits of breastfeeding in fewer infections, increased intelligence, probable protection against overweight and diabetes, and cancer prevention for mothers.

      Via @AndrewAlbertson sur twitter.

    • The Baby-Formula #Crime Ring - The New York Times
      https://www.nytimes.com/interactive/2018/05/02/magazine/money-issue-baby-formula-crime-ring.html

      SOME $4.3 BILLION worth of infant formula was sold in the United States last year, a vast majority of it in powdered form. Between factory and baby aisle, its cheap ingredients (dehydrated milk and vitamins) become steeply, even mysteriously expensive. Basic types run about $15 for a 12.5-ounce can, amounting to perhaps $150 a month for a fully formula-fed infant. Specialty recipes like EleCare can cost two or three times as much. Strict Food and Drug Administration regulations govern formula production, and three companies dominate. Abbott Laboratories, which makes Similac, and Mead Johnson, which makes Enfamil, each control about 40 percent of the market. The Nestlé-owned brand Gerber holds a roughly 15-percent share.

      A market with so little competition is bound to have generous margins, and formula makers have grown richer still because a single buyer accounts for roughly half of all domestic sales: the United States government. The Special Supplemental Nutrition Program for Women, Infants and Children, commonly known as WIC, provides needy mothers with cash assistance for certain foods, including powdered formula. When it began, in 1972, WIC represented a fresh, lush source of inelastic demand, by effectively eliminating from the formula market those customers most sensitive to price. During the ’80s, formula prices rose by more than 150 percent, vastly outpacing increases in milk costs. By the middle of that decade, formula was absorbing 40 percent of WIC’s food budget, prompting shortfalls that shunted many eligible families to a waiting list.

    • Allaitement maternel : Trump défend le lait en poudre | États-Unis
      http://www.lapresse.ca/international/etats-unis/201807/09/01-5188885-allaitement-maternel-trump-defend-le-lait-en-poudre.php

      Attitude criminelle des Etats-Unis : ils défendent les intérêts des fabricants du lait en poudre au détriment de la santé des enfants,

      L’article, paru dans le New York Times, affirme que les délégués américains à une réunion annuelle de l’OMS à Genève en mai ont cherché à supprimer un passage d’une résolution sur l’alimentation du nourrisson et du jeune enfant qui invitait les États membres à « protéger, promouvoir et soutenir » l’allaitement maternel.

      Les Américains auraient fait pression sur l’Équateur afin que le pays renonce à proposer la résolution, et c’est la Russie qui aurait pris le relais. La phrase a finalement été approuvée et figure dans le document disponible aujourd’hui en ligne.

      « L’article du New York Times sur l’allaitement doit être dénoncé. Les États-Unis soutiennent fortement l’allaitement, mais nous pensons que les femmes ne doivent pas se voir interdire l’accès au lait en poudre. De nombreuses femmes ont besoin de cette option à cause de la malnutrition et de la pauvreté », a tweeté Donald Trump.


  • #hacking the Whole #body Approach to #health
    https://hackernoon.com/hacking-the-whole-body-approach-to-health-64b31a8278e?source=rss----3a81

    Eastern and Western approaches to medical practice have often been seen as complete opposites. In fact, many studies have show this view to be folly, and Eastern, also known as Traditional Chinese Medicine (TCM), practices are proven to help alleviate ailments ranging from arthritis, gynecological pain, and migraines to cancer treatment side effects. It has been a mystery why exactly the implementation of acupuncture, yoga, and other TCM practices seem to work, but a new scientific discovery is clearing up the Eastern medicine phenomena that has puzzled Western practitioners.This past March, a team of doctors led by researcher and doctor of pathology Neil Theise of NYU’s Langone School of Medicine discovered what they are referring to as a new organ.It’s name―the interstitium.Using pCLE, (...)

    #healthcare #tech



  • It Was Supposed to Be an Unbiased Study of Drinking. They Wanted to Call It ‘Cheers.’ - The New York Times
    https://www.nytimes.com/2018/06/18/health/nih-alcohol-study.html

    The director of the nation’s top health research agency pulled the plug on a study of alcohol’s health effects without hesitation on Friday, saying a Harvard scientist and some of his agency’s own staff had crossed “so many lines” in pursuit of alcohol industry funding that “people were frankly shocked.”

    A 165-page internal investigation prepared for Dr. Francis Collins, director of the National Institutes of Health, concluded that Kenneth J. Mukamal, the lead investigator of the trial, was in close, frequent contact with beer and liquor executives while designing the study.

    Buried in that document are disturbing examples of the coziness between the scientists and their industry patrons. Dr. Mukamal was eager to allay their concerns, respond to their questions and suggestions, and secure the industry’s buy-in.

    Dr. Mukamal has repeatedly denied communicating with the alcohol industry while planning the trial, telling The Times last year that he had, “literally no contact with the alcohol industry.”

    The study was intended to test the hypothesis that one drink a day is better for one’s heart than none, among other benefits of moderate drinking. But its design was such that it would not pick up harms, such as an increase in cancers or heart failure associated with alcohol, the investigation found.
    Scientists who designed the trial were aware it was not large enough to detect a rise in breast cancer, and acknowledged to grant reviewers in 2016 that the study was focused on benefits and “not powered to identify negative health effects.”

    “Clearly, there was a sense that this trial was being set up in a way that would maximize the chances of showing a positive effect of alcohol,” Dr. Collins said last week as he accepted his advisers’ recommendation to terminate the trial.

    “Understandably, the alcoholic beverage industry would like to see that.”

    If the study failed to find health benefits in moderate drinking but provided no evidence of harm, the results still would be a boon for the beverage makers. The findings would counter a 2014 World Health Organization edict that no level of alcohol consumption is safe because it raises the risk of cancer.

    #Santé_publique #Alcool #Conflit_intérêt


  • Back pain: how to live with one of the world’s biggest health problems | Society | The Guardian
    https://www.theguardian.com/society/2018/jun/14/back-pain-how-to-live-with-one-of-the-worlds-biggest-health-problems

    This month, the Lancet published a series of three papers written by a large, international group of experts who came together to raise awareness of the extent of the problem of low back pain and the evidence for recommended treatments. The authors were scathing about the widespread use of “inappropriate tests” and “unnecessary, ineffective and harmful treatments”.

    The papers tell us low back pain is an “extremely common symptom, experienced by people of all ages”, although it peaks in mid-life and is more common in women than in men. There are 540 million people affected globally at any one time and it is the main cause of disability worldwide.

    The six-year investigation that began as an attempt to find relief from her own pain and ended up exposing an exploitative, corrupt and evidence-free $100bn industry, is fittingly described in the title of her book: Crooked.

    The camera lies … MRI scans show up disc degeneration but unfortunately most people will have some. Photograph: HadelProductions/Getty Images

    The proliferation of unnecessary and risky interventions has been far worse in the US, with its insurance-based healthcare system, than in the NHS. But the UK is far from immune. When a healthcare system functions as a marketplace, there will inevitably be incentives for certain treatments to be pursued over others, for services that can generate a surplus. It is a struggle for patients and clinicians everywhere to resist pain medication that is incredibly effective in the short term, even if it is incredibly harmful in the long term.

    “Nearly everybody gets back pain at some point in their life,” says Martin Underwood, co-author of the Lancet series, a GP and a professor at Warwick Medical School. “For most people, it’s a short-term episode that will resolve over a period of days or weeks, without the need for any specific treatment. They catch or twist or stretch something, and it’s awful, and then it gets better.” Of those who experience a new episode of back pain, under 1% will have serious causes that need specific treatment for issues such as cancer in the spine, a fracture, diseases or infection, he says. But there is another group, in which, “after the natural period of healing – normally six weeks for most things – people go on to get pain lasting months and years, which can be very disabling, even though the original cause of the pain is no longer there. We would label this as nonspecific low back pain, simply because we don’t know what is causing the pain.”

    “At best, these spine surgeons define success as a 38% improvement in pain and function,” says Ramin, “but if a hip or a knee surgeon had a 38% success rate, that physician would no longer do that surgery. And 38%? I think that’s really optimistic.” In her book, she describes the scandal of the Pacific Hospital in Long Beach, California, which carried out more than 5,000 spinal fusion surgeries. “Surgeries were being performed on large numbers of patients who were often immigrants – Spanish-speaking labourers – and being billed to workers’ compensation insurance or public health insurance. Could you do worse than butcher these Latino field workers who don’t understand what’s happening to them, but are being told they can get free medical care?”

    We like to think that this could never happen in the UK, and Underwood admits there is a huge difference between the two healthcare systems. “Most spinal surgeons in the UK will avoid operating for nonspecific low back pain because they’re aware of all these problems,” he says. “But there is still pressure from patients for something to make them better, and some people are still getting operated on. My advice for anybody is: don’t have surgery for back pain unless there is a clear, specific indication.”

    When I ask Underwood what works, he tells me: “Whatever you do for a patient at a time when their back is really bad, the chances are they’re going to be a lot better three weeks later. So we treat people and we see them getting better and we ascribe their improvement to the treatment we’ve given, but we know that natural improvement over time is always much larger than the positive effect you get from the treatment.” The evidence is strongest for therapist-delivered interventions such as the cognitive behavioural approach, based on the same principles as CBT, exercise treatment and physiotherapy. He has also worked on a trial that showed training physiotherapists to deliver the cognitive behavioural approach in a group, combining movement and reassurance about movement, is helpful to patients and could be delivered in the NHS at low cost.

    #Mal_de_dos #Opioides #Médecine


  • What consumer DNA data can and can’t tell you about disease risk | Science News
    https://www.sciencenews.org/article/health-dna-genetic-testing-disease

    False alarm
    A clinical lab checked worrisome results that people received from consumer DNA testing companies. Of the variants flagged as harmful, 40 percent were false positives. All but one of the bad calls were in cancer risk genes: BRCA1, BRCA2, TP53, CHEK2, MLH1 and ATM.

    Risks explained
    Customers of 23andMe who want to unlock information on their breast cancer risk must click through several screens of information before learning the result. This screen explains that risk goes beyond the three variants reported.