medicalcondition:cancer

PLOS Neglected Tropical Diseases: Diseases Neglected by the Media in Espírito Santo, Brazil in 2011–2012
▻http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0004662

Abstract

Background
The aims of the present study were to identify and analyse the Diseases Neglected by the Media (DNMs) via a comparison between the most important health issues to the population of Espírito Santo, Brazil, from the epidemiological perspective (health value) and their effective coverage by the print media, and to analyse the DNMs considering the perspective of key journalists involved in the dissemination of health topics in the state media.

Methodology
Morbidity and mortality data were collected from official documents and from Health Information Systems. In parallel, the diseases reported in the two major newspapers of Espírito Santo in 2011–2012 were identified from 10,771 news articles. Concomitantly, eight interviews were conducted with reporters from the two newspapers to understand the journalists’ reasons for the coverage or neglect of certain health/disease topics.

Principal Findings
Quantitatively, the DNMs identified diseases associated with poverty, including tuberculosis, leprosy, schistosomiasis, leishmaniasis, and trachoma. Apart from these, diseases with outbreaks in the period evaluated, including whooping cough and meningitis, some cancers, respiratory diseases, ischaemic heart disease, and stroke, were also seldom addressed by the media. In contrast, dengue fever, acquired immune deficiency syndrome (AIDS), diabetes, breast cancer, prostate cancer, tracheal cancer, and bronchial and lung cancers were broadly covered in the period analysed, corroborating the tradition of media disclosure of these diseases. Qualitatively, the DNMs included rare diseases, such as amyotrophic lateral sclerosis (ALS), leishmaniasis, Down syndrome, and verminoses. The reasons for the neglect of these topics by the media included the political and economic interests of the newspapers, their editorial line, and the organizational routine of the newsrooms.

Conclusions
Media visibility acts as a strategy for legitimising priorities and contextualizing various realities. Therefore, we propose that the health problems identified should enter the public agenda and begin to be recognized as legitimate demands.

Winning the Cancer War: Start With the Deepest Intelligence - Facts So Romantic
▻http://nautil.us/blog/winning-the-cancer-war-start-with-the-deepest-intelligence

http://static.nautil.us/8564_621eb0b827c09dd1804e87bd74f79383.jpg

This is the first in a three-part series, “Winning the Cancer War,” by Patrick Soon-Shiong, MD, FRCS(C), FACS In 2003, government agencies proclaimed we solved cancer because we solved the human genome. We thought we could halt cancer in its tracks by targeting mutations in our DNA and stopping those “cancer drivers.” This spurred the great genomics buildout over the last ten years. Hundreds of academic medical centers and companies began developing their own gene panels—everything from 40 DNA gene panel to 500 gene panels, from breast cancer panels to lung cancer panels, and everything in between—all in a tremendous race to treat cancer with targeted drugs. Large pharma and biotechs joined the bandwagon. They invested billions of dollars and utilized insights from limited gene panels as (...)

“They really don’t want this out”: The biggest Iraq War scandal that nobody’s talking about - Salon.com
▻http://www.salon.com/2016/02/16/burn_pits

Thousands of soldiers have suffered similar fates since serving in the vicinity of the more than 250 military burn pits that operated at bases throughout Iraq and Afghanistan. Many who haven’t succumbed to their illnesses yet have passed along the legacy of their poisoning to their children. “The rate of having a child with birth defects is three times higher for service members who served in those countries,” according to the book.

The impact on local civilian populations is even more widespread. Although collecting data in these war-ravaged areas is extremely difficult, the studies that have been conducted reveal sharp increases in cancer and leukemia rates and skyrocketing numbers of birth defects. The toxic legacies of these burn pits will likely continue to devastate these regions for decades.

So what are the “burn pits”? When the U.S. military set up a base in Iraq or Afghanistan, instead of building incinerators to dispose of the thousands of pounds of waste produced each day, they burned the garbage in big holes in the ground. The garbage they constantly burned included “every type of waste imaginable” including “tires, lithium batteries, asbestos insulation, pesticide containers, Styrofoam, metals, paints, plastic, medical waste and even human corpses.”

Here’s where the story gets even more infuriating. As a result of the privatization of many aspects of military operations, the burn pits were operated by Kellogg, Brown, and Root (KBR), a former subsidiary of #Halliburton, the company where Dick #Cheney was CEO before ascending to the White House. During the Bush administration, Halliburton made nearly $40 billion from lucrative government contracts (despite many corruption scandals), Dick Cheney and his corporate allies got incredibly rich, and the soldiers whose lives have likely been destroyed by this reckless operation… are pretty much screwed.

#fosses_de_brulage #crimes #états-unis #Irak

The High Cost of Cancer Care May Take Physical and Emotional Toll on Patients - WSJ
▻http://www.wsj.com/articles/the-high-cost-of-cancer-care-may-take-physical-and-emotional-toll-on-patients-1

http://si.wsj.net/public/resources/images/HE-AA188A_TOXIC_16U_20160215164809.jpg

#santé #cancer #faillite #États-Unis

L’Europe continue de bricoler face à l’arrivée de migrants
▻https://www.mediapart.fr/journal/international/120216/leurope-continue-de-bricoler-face-larrivee-de-migrants

Ce début d’année 2016 montre que les arrivées de migrants ne ralentissent pas, au contraire. Après des mois d’atermoiements, l’Union européenne continue pourtant de bricoler. Dernière nouvelle en date : des navires de l’OTAN vont intervenir en mer Égée.

#International #Alep #Allemagne #asile #europe #Grèce #hotspot #Lesbos #Otan #réfugiés #Syrie #turquie #union_européenne

Americans more likely to die younger than people in other developed nations
▻http://boingboing.net/2016/02/09/americans-die-younger-than-oth.html

http://media.boingboing.net/wp-content/uploads/2015/06/giphy-8.gif

#Etats-unis

A Single Cell Shines New Light on How #Cancers Develop - The New York Times
▻http://www.nytimes.com/2016/01/29/health/how-skin-cancer-develops-melanoma-zebra-fish.html?smid=tw-nythealth&smtyp=c

“More and more data suggest that just having mutations is not sufficient to cause cancer,” said Dr. Kornelia Polyak, a breast cancer researcher at the Dana Farber Cancer institute, who was not associated with the new study. “You need the right context.”

That was where Dr. Zon and his colleagues began 10 years ago. They were investigating melanoma by creating it in zebra fish, tiny transparent creatures that allow researchers to see cells and organs without cutting the fish open. The researchers put human BRAF and P53 genes in every melanocyte, the pigmented skin cells, of the fish. If genes were all that was needed for cancer, the fish would explode with melanoma. But the researchers found only one to three melanomas per fish.

“That told us there has to be an additional event,” Dr. Zon said.

By luck, they found it. The pigmented skin cells that became cancerous had turned on a gene, crestin, that is normally activated only in cells that are part of the neural crest, a group of cells pinched off early in embryonic life from a region adjacent to the brain. These primitive cells, depending on where they are in the embryo, can turn into pigmented skin cells or a variety of other types of cells, like those that make up bones and teeth, the covering of the brain or those that sheath and insulate nerve cells. Once cells develop into their mature tissue type — pigmented skin cell, bone or tooth, for example — the crestin gene shuts down. Those pigmented skin cells in the fish that had an active crestin gene had reverted back to that primitive state when they were malleable, their fates still wide open.

Causes of Death | FlowingData
▻http://flowingdata.com/2016/01/05/causes-of-death

http://i2.wp.com/flowingdata.com/wp-content/uploads/2016/01/Cause-of-Death-by-Age.png?fit=1200%2C609

There are many ways to die. Cancer. Infection. Mental. External. The Centers for Disease Control and Prevention classifies the ways into 113 causes, which are grouped into 20 categories. The CDC’s Underlying Cause of Death database provides estimates for the number of people who die due to each of the causes.

Feeling like a Grinch ? At least it won’t shorten your life | Fox News
▻http://www.foxnews.com/health/2015/12/10/feeling-like-grinch-at-least-it-wont-shorten-your-life.html

Previous studies have linked happiness to longevity but researchers now say there’s no such scientific connection. So while being sick makes you unhappy, just being grouchy isn’t enough to make you ill or shorten your life.

The results are based on questionnaires from more than 715,000 British women aged 50 to 69 who were enrolled in a national breast cancer screening program in the late 1990s.

The women were asked things like how often they felt happy and how healthy they were. Nearly 40 percent of the women said they were happy most of the time while 17 percent said they were unhappy. After a decade of tracking the women, 4 percent had died.

Scientists found the death rate among unhappy women was the same as those who were happy. The research was published online Wednesday in the medical journal Lancet.

Cancer control in Africa - The Lancet (2013)
▻http://www.thelancet.com/series/cancer-control-in-africa

the proportion of the overall disease burden in sub-Saharan Africa attributable to cancer is rising, and the region is predicted to have a greater than 85% increase in cancer burden by 2030. This Series of seven papers focuses on cancer control in Africa, outlining the current situation, detailing barriers to care, and presenting ideas to advance cancer care and control in the region.

#cancer #santé_publique

Sur le phénomène des #journaux_prédateurs (#spam scientifique) :

Journal Accepts Paper Reading “Get Me Off Your Fucking Mailing List”
▻http://www.iflscience.com/technology/journal-accepts-paper-reading-get-me-your-fucking-mailing-list
▻http://www.iflscience.com/sites/www.iflscience.com/files/styles/ifls_large/public/blog/%5Bnid%5D/Screen_Shot_2014-11-21_at_10.19.51_AM.0.0.jpg?itok=4MeXBtp6

A paper that largely consists of the words “Get me off your fucking mailing list” repeated 863 times has been accepted by a journal that claims to be peer reviewed. The move might appear to offer hope to scientists struggling to get marginal work published, but really just exposes the extent of scam publications pretending to be contributing to science.

et un blog qui recense ces faux journaux qui permettent contre rémunération d’avoir des “publi” que personne ne lira jamais.

▻http://scholarlyoa.com

#bibliométrie #recherche via @anne

3rd Palestinian dies from clashes with Israeli forces
Nov. 13, 2015 6:46 P.M. (Updated: Nov. 13, 2015 7:43 P.M.)
▻http://www.maannews.com/Content.aspx?id=768817

RAMALLAH (Ma’an) — Israeli forces shot and killed a 22-year-old Palestinian in the Ramallah-area village of Budrus, the third to die on Friday from live Israeli fire during clashes in the occupied West Bank.

The Palestinian Ministry of Health told Ma’an that Lafi Yusif Awad was brought to the Palestine Medical Complex in Ramallah in critical condition and pronounced dead shortly after.

Awad was shot by Israeli forces in the left side of his abdomen when intense clashes erupted in the village, and several others were injured, the ministry added.

An Israeli army spokesperson told Ma’an that dozens of Palestinians “violently rioted” in Budrus, “attempting to damage the security fence, hurling rocks and firebombs.”

The forces arrived to “arrest a main instigator,” when a Palestinian attempted to steal a soldier’s weapon, the spokesperson said.

Israeli forces then “fired at the attacker,” and he was evacuated from the scene by the Palestinian Red Crescent, the spokesperson added.

Budrus — bordered on two sides by the Israeli separation wall — was one of several towns in the occupied West Bank where Palestinians clashed with Israeli forces on Friday.

#Palestine_assassinée

Extremism & Incitement to Racial Hatred: Senior Israeli Officials in Their Own Words
▻http://imeu.org/article/extremism-incitement-to-racial-hatred-senior-israeli-officials-in-their-own

http://imeu.org/uploads/imagefiles/article/_featured/MAGNEHAGESAETERGasTheArabsGraffitiHebron.jpg

“A Jew always has a much higher soul than a gentile, even if he is a homosexual.”
– Then-deputy minister of religious services and current deputy minister of defense, Rabbi Eli Ben-Dahan, 2013.

“I am happy to be a fascist!”
– Miri Regev, current minister of culture and sport, 2012.

“[There are] 92,000 families in Israel in which one of the partners is not Jewish - we have a real problem that we have to deal with."
– Tzipi Hotovely, current deputy foreign minister, 2011.

“The Palestinian threat harbors cancer-like attributes that have to be severed. There are all kinds of solutions to cancer. Some say it’s necessary to amputate organs but at the moment I am applying chemotherapy.”
– Then-general and current defense minister, Moshe Yaalon, 2002.

“[The way to deal with Palestinians is to] beat them up, not once but repeatedly, beat them up so it hurts so badly, until it’s unbearable.”
– Benjamin Netanyahu, current prime minister, while in the opposition following his first term as prime minister, caught on video speaking to Israeli settlers, 2001.

#sionisme #sioniste #Israel #Israël #etat_raciste

Le ver solitaire transmet son cancer au porteur humain.

A Tapeworm With Cancer Gave Its Tumors to Someone - NBC News
▻http://www.nbcnews.com/health/health-news/tapeworm-cancer-gave-its-tumors-someone-n457586

Tapeworms are bad enough. They get inside people, lay their eggs, and cause symptoms such as diarrhea and weakness. And they can infest a body for a lifetime.

But doctors were stunned to find out they can do something worse: infect people with tumors.

La publication et son résumé (qui fait la une du NEJM). L’article entier est accessible.
Malignant Transformation of Hymenolepis nana in a Human Host — NEJM
▻http://www.nejm.org/doi/full/10.1056/NEJMoa1505892#t=abstract

Neoplasms occur naturally in invertebrates but are not known to develop in tapeworms. We observed nests of monomorphic, undifferentiated cells in samples from lymph-node and lung biopsies in a man infected with the human immunodeficiency virus (HIV). The morphologic features and invasive behavior of the cells were characteristic of cancer, but their small size suggested a nonhuman origin. A polymerase-chain-reaction (PCR) assay targeting eukaryotes identified Hymenolepis nana DNA. Although the cells were unrecognizable as tapeworm tissue, immunohistochemical staining and probe hybridization labeled the cells in situ. Comparative deep sequencing identified H. nana structural genomic variants that are compatible with mutations described in cancer. Invasion of human tissue by abnormal, proliferating, genetically altered tapeworm cells is a novel disease mechanism that links infection and cancer.

Costs for Dementia Care Far Exceeding Other Diseases, Study Finds
▻http://www.nytimes.com/2015/10/27/health/costs-for-dementia-care-far-exceeding-other-diseases-study-finds.html

The study looked at patients on Medicare. The average total cost of care for a person with dementia over those five years was $287,038. For a patient who died of heart disease it was $175,136. For a cancer patient it was $173,383. Medicare paid almost the same amount for patients with each of those diseases — close to $100,000 — but dementia patients had many more expenses that were not covered.

On average, the out-of-pocket cost for a patient with dementia was $61,522 — more than 80 percent higher than the cost for someone with heart disease or cancer. The reason is that dementia patients need caregivers to watch them, help with basic activities like eating, dressing and bathing, and provide constant supervision to make sure they do not wander off or harm themselves. None of those costs were covered by Medicare.

#démence #coût #santé

Why Is the World Health Organization so Bad at Communicating #Cancer Risk? - The Atlantic
▻http://www.theatlantic.com/health/archive/2015/10/why-is-the-world-health-organization-so-bad-at-communicating-cancer-risk/412468

The International Agency of Research into Cancer (IARC), an arm of the World Health Organization, is notable for two things. First, they’re meant to carefully assess whether things cause cancer, from pesticides to sunlight, and to provide the definitive word on those possible risks.

Second, they are terrible at communicating their findings.

Their failings are in full view today. (...)

Here’s the thing: These classifications are based on strength of evidence not degree of risk.

#santé #communication #fiasco

American Cancer Society, in a Shift, Recommends Fewer Mammograms
▻http://www.nytimes.com/2015/10/21/health/breast-cancer-screening-guidelines.html

The changes reflect increasing evidence that mammography is imperfect, that it is less useful in younger women, and that it has serious drawbacks, like false-positive results that lead to additional testing, including biopsies.

But the organization’s shift seems unlikely to settle the issue. Some other influential groups recommend earlier and more frequent screening than the cancer society now does, and some recommend less, leaving women and their doctors to sort through the conflicting messages and to figure out what makes the most sense for their circumstances.

Selon Benjamin Netanyahu, « Hitler ne voulait pas exterminer les Juifs » - SudOuest.fr
▻http://www.sudouest.fr/2015/10/21/selon-benjamin-netanyahu-hitler-ne-voulait-pas-exterminer-les-juifs-2161237

"Hitler ne voulait pas exterminer les Juifs à cette époque, il voulait expulser les Juifs. Et Haj Amin al-Husseini est allé voir Hitler et lui a dit : « Si vous les expulsez, il vont tous venir ici (en Palestine) ». « Alors que devrais-je faire d’eux ? », a demandé Hitler. « Brûlez-les », lui a-t-il répondu."

via @JulienSalingue
▻https://twitter.com/juliensalingue/status/656745798760316928

New #cancer modeling videos - Business Insider
▻http://www.businessinsider.com/new-cancer-modeling-videos-2015-9

http://static2.businessinsider.com/image/55e9d59fdd089594398b4654/an-awesome-new-technique-is-giving-doctors-an-unprecedented-look-at-cancer.jpg

After being treated, the tumor areas that grow back tend to be the ones that have genetic mutations that allow them to resist that treatment. The researchers say that modeling and knowing the genetics of the tumors could help doctors predict how cancers will respond to different combinations of therapies, allowing them to develop treatment strategies specifically targeted to each cancer.

▻https://www.youtube.com/watch?v=lpytoIxRu0o

#santé

Ex-hedge funder buys rights to AIDS drug and raises price from $13.50 to $750 per pill
▻http://www.rawstory.com/2015/09/ex-hedge-funder-buys-rights-aids-drug-and-raises-price-from-13-50-to-750-p

http://www.rawstory.com/wp-content/uploads/2015/09/turing_exec-800x430.jpg

Drug Goes From $13.50 a Tablet to $750, Overnight
▻http://www.nytimes.com/2015/09/21/business/a-huge-overnight-increase-in-a-drugs-price-raises-protests.html

Turing’s price increase is not an isolated example. While most of the attention on pharmaceutical prices has been on new drugs for diseases like cancer, hepatitis C and high cholesterol, there is also growing concern about huge price increases on older drugs, some of them generic, that have long been mainstays of treatment.

#pharma « #marché » #santé #prix #médicaments #Etats-Unis

Exclusive: 50 Spies Say ISIS Intelligence Was Cooked - The Daily Beast
►http://www.thedailybeast.com/articles/2015/09/09/exclusive-50-spies-say-isis-intelligence-was-cooked.html

It’s being called a ‘revolt’ by intelligence pros who are paid to give their honest assessment of the ISIS war—but are instead seeing their reports turned into happy talk.
More than 50 intelligence analysts working out of the U.S. military’s Central Command have formally complained that their reports on ISIS and al Qaeda’s branch in Syria were being inappropriately altered by senior officials, The Daily Beast has learned.

The complaints spurred the Pentagon’s inspector general to open an investigation into the alleged manipulation of intelligence. The fact that so many people complained suggests there are deep-rooted, systemic problems in how the U.S. military command charged with the war against the self-proclaimed Islamic State assesses intelligence.

“The cancer was within the senior level of the intelligence command,” one defense official said.

Two senior analysts at CENTCOM signed a written complaint sent to the Defense Department inspector general in July alleging that the reports, some of which were briefed to President Obama, portrayed the terror groups as weaker than the analysts believe they are. The reports were changed by CENTCOM higher-ups to adhere to the administration’s public line that the U.S. is winning the battle against ISIS and al Nusra, al Qaeda’s branch in Syria, the analysts claim.

Doubt Is Raised Over Value of Surgery for Breast Lesion at Earliest Stage - The New York Times
▻http://www.nytimes.com/2015/08/21/health/breast-cancer-ductal-carcinoma-in-situ-study.html?_r=0

A majority of the 100,000 patients in the database the researchers used, from a national cancer registry, had lumpectomies, and nearly all the rest had mastectomies, the new study found. Their chance of dying of breast cancer in the two decades after treatment was 3.3 percent, no matter which procedure they had, about the same as an average woman’s chance of dying of breast #cancer, said Dr. Laura J. Esserman, a breast cancer surgeon and researcher at the University of California, San Francisco, who wrote an editorial accompanying the study.

#santé #chirurgie #cancer_du_sein

Early-Stage Breast Condition May Not Require Cancer Treatment - The New York Times
▻http://www.nytimes.com/2015/08/21/health/breast-cancer-ductal-carcinoma-in-situ-study.html

As many as 60,000 American women each year are told they have a very early stage of breast cancer — Stage 0, as it is commonly known — a possible precursor to what could be a deadly tumor. And almost every one of the women has either a lumpectomy or a mastectomy, and often a double mastectomy, removing a healthy breast as well.

Yet it now appears that treatment may make no difference in their outcomes. Patients with this condition had close to the same likelihood of dying of breast cancer as women in the general population, and the few who died did so despite treatment, not for lack of it, researchers reported Thursday in JAMA Oncology.

Their conclusions were based on the most extensive collection of data ever analyzed on the condition, known as ductal carcinoma in situ, or D.C.I.S.: 100,000 women followed for 20 years.

#cancer #femmes #mastectomie #recherche #santé #médecine via @isskein

Price & Value of #Cancer Drug | Memorial Sloan Kettering Cancer Center
▻https://www.mskcc.org/research-areas/programs-centers/health-policy-outcomes/cost-drugs

Cost of one month of treatment for an adult for each new cancer drug approved by the United States Food and Drug Administration, based on Medicare reimbursement rates and by year of drug approval.

https://www.mskcc.org/sites/default/files/node/25097/images/chemo-prices-graph-7.2.15.jpg

et un article du WSJ qui en parle (pas lu)
▻http://www.wsj.com/articles/how-much-should-cancer-drugs-cost-1434640914

#pharma #prix #santé