industryterm:cancer prevention

U.S. Opposition to Breast-Feeding Resolution Stuns World Health Officials - The New York Times
►https://www.nytimes.com/2018/07/08/health/world-health-breastfeeding-ecuador-trump.html

https://static01.nyt.com/images/2018/07/09/business/09breastfeeding-1-sub-2/merlin_74866264_0e99440c-95bc-40f5-8b74-c30bc48e93e4-facebookJumbo.jpg

American officials sought to water down the resolution by removing language that called on governments to “protect, promote and support breast-feeding” and another passage that called on policymakers to restrict the promotion of food products that many experts say can have deleterious effects on young children.

When that failed, they turned to threats, according to diplomats and government officials who took part in the discussions. Ecuador, which had planned to introduce the measure, was the first to find itself in the cross hairs.

The Americans were blunt: If Ecuador refused to drop the resolution, Washington would unleash punishing trade measures and withdraw crucial military aid. The Ecuadorean government quickly acquiesced.

#Etats-Unis #corrompu #corruption #lobbying #gangsters #mafia #sans_vergogne

Do naked mole rats hold the answers to cancer prevention and aging?
▻https://massivesci.com/articles/naked-mole-rats-aging-cancer

Their genes don’t create faulty cells the way ours do

https://takeshape-prod.imgix.net/fd194db7-7b25-4b5a-8cc7-da7f31fab475%2Fdev%2F8fb9977f-a609-4809-841f-4a8ecb557823%2F30223548792_bb652bfae3_o.jpg?auto=compress%2Cformat&crop=faces&fit=crop&fm=jpg&h=600&q=75&w=900

Oleocanthal rapidly and selectively induces cancer cell death via lysosomal membrane permeabilization

▻http://www.tandfonline.com/doi/full/10.1080/23723556.2015.1006077

Extra-virgin olive oil (EVOO), a central component of the Mediterranean diet, contains an abundance of phenolic antioxidants that are potent inhibitors of reactive oxygen species and is associated with a reduced risk for several types of human cancer.1 Giacosa A, Barale R, Bavaresco L, Gatenby P, Gerbi V, Janssens J, Johnston B, Kas K, La Vecchia C, Mainguet P, et al. Cancer prevention in Europe: the Mediterranean diet as a protective choice. Eur J Cancer Prev 2013; 22:90–5; PMID:22644232; ▻http://dx.doi.org/10.1097/CEJ.0b013e328354d2d7[CrossRef], [PubMed], [Web of Science ®], [Google Scholar] Polyphenolic secoiridoids of EVOO have been shown to decrease viability of HER2-overexpressing breast cancer cells by selectively inducing apoptotic cell death.2 Menendez JA, Vazquez-Martin A, Colomer R, Brunet J, Carrasco-Pancorbo A, Garcia-Villalba R, Fernandez-Gutierrez A, Segura-Carretero A. Olive oil’s bitter principle reverses acquired autoresistance to trastuzumab (Herceptin) in HER2-overexpressing breast cancer cells. BMC Cancer 2007; 7:80; PMID:17490486; ▻http://dx.doi.org/10.1186/1471-2407-7-80[CrossRef], [PubMed], [Web of Science ®], [Google Scholar] (-)-Oleocanthal (OC), a di-aldehydic form of ligostride aglycone that has been isolated from EVOO, possesses a wide range of biological effects. Previous studies have reported its activity as a potent antioxidant; a nonsteroidal anti-inflammatory agent that inhibits COX-1 and COX-2; a neuroprotectant that alters the structure and function of the neurotoxins β-amyloid and Tau, which are associated with the debilitating effects of Alzheimer disease; an inhibitor of proliferation, migration, and invasion of human breast and prostate cancer cells through c-Met inhibition; an inhibitor of AMPK in colon cancer cells; and an inhibitor of macrophage inflammatory protein-1α in multiple myeloma.3-8 Beauchamp GK, Keast RS, Morel D, Lin J, Pika J, Han Q, Lee CH, Smith AB, Breslin PA. Phytochemistry: ibuprofen-like activity in extra-virgin olive oil. Nature 2005; 437:45–6; PMID:16136122; ▻http://dx.doi.org/10.1038/437045a
Busnena BA, Foudah AI, Melancon T, El Sayed KA. Olive secoiridoids and semisynthetic bioisostere analogues for the control of metastatic breast cancer. Bioorg Med Chem 2013; 21:2117–27; PMID:23403296; ▻http://dx.doi.org/10.1016/j.bmc.2012.12.050
Elnagar AY, Sylvester PW, El Sayed KA. (-)-Oleocanthal as a c-Met inhibitor for the control of metastatic breast and prostate cancers. Planta Med 2011; 77:1013–9; PMID:21328179; ▻http://dx.doi.org/10.1055/s-0030-1270724
Monti MC, Margarucci L, Riccio R, Casapullo A. Modulation of tau protein fibrillization by oleocanthal. J Nat Prod 2012; 75:1584–8; PMID:22988908; ▻http://dx.doi.org/10.1021/np300384h
Scotece M, Gomez R, Conde J, Lopez V, Gomez-Reino JJ, Lago F, Smith AB 3rd, Gualillo O. Oleocanthal inhibits proliferation and MIP-1a expression in human multiple myeloma cells. Curr Med Chem 2013; 20:2467–75; PMID:23521677; ▻http://dx.doi.org/10.2174/0929867311320190006
Pitt J, Roth W, Lacor P, Smith AB 3rd, Blankenship M, Velasco P, De Felice F, Breslin P, Klein WL. Alzheimer’s-associated Ab oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal. Toxicol Appl Pharmacol 2009; 240:189–97; PMID:19631677; ▻http://dx.doi.org/10.1016/j.taap.2009.07.018

To investigate the anticancer effects of OC, we examined its effect on the viability and survival of cancerous and non-cancerous cells.

#cancer_recherche #anticancer #huile_d'olive #oléocanthal #inhibiteurs

Heirloom Tomatoes — Heritage Food Crops Research Trust
▻http://heritagefoodcrops.org.nz/heirloom-tomatoes

This research is looking to find the best open-pollinated tomato varieties in the world for human health, particularly those highest in lycopene for cancer prevention.
The research is also seeking to determine whether hybrid tomato varieties (and vegetables in general) are nutritionally deficient in comparison with traditional open-pollinated heirloom varieties.

#légumes #tomates #nutrition #santé #alimentation

Grim Cancer Statistics From China - Businessweek
▻http://www.businessweek.com/articles/2013-04-09/grim-cancer-statistics-from-china

Cancer is the leading cause of death in Beijing, according to data released by the city’s Cancer Prevention and Control Research Office. A division of the Chinese Academy of Medical Sciences, the center has found that since 2007, more Beijingers have died each year from cancer than from cardiovascular disease, previously the top killer.

Exposure to environmental pollution, as well as changing diet and more sedentary lifestyles, are contributing factors, says the center’s Deputy Director Wang Ning. Noting that the number of cancer diagnoses is rising in both rural and urban China, he told China Newsweek (no relation to U.S. Newsweek/Dailybeast) on April 7, “In the next 10 years, the cancer burden won’t be lowered – we can only hope to eventually stabilize it.” His research team estimates by 2020, the total number of cancer deaths in China will climb from about 2.5 million to 3 million annually.

Rising vehicle emissions pose health hazards in large Chinese cities: Beijing’s Environmental Protection Bureau told the Beijing News last week that levels of two major air pollutants – nitrogen dioxide and PM10 (particulate matter less than 10 micrometers in diameter) – had risen steeply in the last year. The average levels of those two pollutants were nearly 30 percent higher in the first three months of 2013 than in the same months of 2012. (Meanwhile levels of sulfur dioxide, a third major pollutant, decreased slightly.) Nationwide, China just experienced its smoggiest March in 52 years, the China Meteorological Administration announced on April 1.

While smoggy cities attract frequent headlines, the risks from pollution are often most acute in small towns and villages, where environmental regulators have little authority to rein in polluting industries that contribute substantially to the local tax bases. In February, China’s national Ministry of Environmental Protection for the first time acknowledged the existence of long-rumored “cancer villages” in China. “Toxic chemicals have caused many environmental emergencies,” as the text of a new plan for controlling hazardous chemicals put it. “There are even some serious cases of health and social problems, like the emergence of cancer villages in individual regions.”

The increased transparency in China about worsening pollution is a sliver of a silver lining.